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Protox Therapeutics web based tox prediction tool
Web Based Tox Prediction Tool, supplied by Protox Therapeutics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/web-based+tool/based+prediction+tool+tox+web/pm42041868-66-13-18
Average 86 stars, based on 1 article reviews
web based tox prediction tool - by Bioz Stars, 2026-10
86/100 stars

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Article Title: In Silico Approach for Fluorene Biodegradation, and the Impacts of Derivatives on the Environment and Health.
Article Snippet: The toxicity level of fluorene and its intermediate derivatives was determined using the web-based TOX-PREDICTION tool of the ProTox 3.0—Prediction of Toxicity of Chemicals server (https://tox.charite.de/protox3/index.php?site=compound_ input (accessed on 20 October 2025)) [36].

Article Title: 3,5-Disubstituted-thiazolidine-2,4-dione hybrids as antidiabetic agents: Design, synthesis, in-vitro and In vivo evaluation.
Article Snippet: Diabetes is one of the fastest-growing metabolic disorders, nearly doubling the number of patients each year.. There are different treatment approaches available for the management of diabetes, which lacks due to their side effects.. The inhibition of enzymes involved in the metabolism of complex polysaccharides to monosaccharides has proven beneficial in patients with type 2 diabetes mellitus.

Article Title: In silico approaches for the identification of novel FGFR1 inhibitor in cancer: A fragment-based De novo drug designing guided virtual screening approach.
Article Snippet: The fibroblast growth factor receptor 1 (FGFR1) plays a crucial role in cancer development and progression, primarily through mechanisms involving carcinogenesis and angiogenesis.. Aberrant FGFR1 signalling has been implicated in various cancers, including lung, breast, neck and urothelial carcinoma.. Despite the recognized oncogenic potential of FGFR1, therapeutic strategies targeting its kinase domain remain inadequately explored.

Article Title: In Silico Approach for Fluorene Biodegradation, and the Impacts of Derivatives on the Environment and Health
Article Snippet: The toxicity level of fluorene and its intermediate derivatives was determined using the web-based TOX-PREDICTION tool of the ProTox 3.0—Prediction of Toxicity of Chemicals server ( https://tox.charite.de/protox3/index.php?site=compound_input (accessed on 20 October 2025)) [ ].


Article Title: Comparative chemical composition and pesticidal evaluation of Acorus calamus accessions collected from different geographical locations
Article Snippet: Excretion and toxicity were predicted using the Web-based online tool Protox II, where LD50 values and toxicological parameters (hepatotoxicity, carcinogenicity, mutagenicity, and cytotoxicity) were predicted for the main compounds that did not show toxicity [60].

Drug discovery:

Article Title: Therapeutic and Safety Evaluation of Enhydra fluctuans Lour. and Ipomoea aquatica Forssk. as Acetylcholinesterase, Butyrylcholinesterase, β-Secretase, and CytochromeP450 Inhibitors Using In Vitro and UPLC-QTOF-MS-Based Molecular Docking and Dynamic Simulation Study.
Article Snippet: Considering the multi-targeted drug approach, Enhydra fluctuans and Ipomoea aquatica were comprehensively investigated for their acetylcholinesterase, butyrylcholinesterase, and β-secretase enzyme inhibitory potential, which are linked to Alzheimer’s disease.. The results showed that I. aquatica produced more prominent anti-cholinesterase potential compared to E. fluctuans.. But E. fluctuans showedmore potent BACE1 inhibitory potential compared to I. aquatica.



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